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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '965b59fcda3a181aceb207110a0a097349bab5b382d8c3e93000f59b329853ce' 
  AND token = '1aM/UHv/JTf8EH1zItZjtKI+MkisoELI9leWD4MFBxQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}