SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '30421617cb90fcff1bb06ddbcf45f80617fcd4591539b7ee513ebb3b0e4900ce' 
  AND token = 'UeS0pAXkxvU4i+y8Pn4ayfFk7GR+hqpamgpE3tff/JU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}