SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06d9652ab761c7bef140207f5bbdf99fd22d56b0261ca957cd3c2dac598d00b0' 
  AND token = 'eTnxiVoJ295rm8mVdL9yfZLe62D0/RucZJecLUAm6Ds=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}