SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a1142cd7bd3c1191b7ca6139f3d42622ba00c6c6ea3ddb9f8b6ae85f1ffb563' 
  AND token = '8fYw1busjH6giDZNC6+gHXKF9S3NDBuwMKWKqzzPNN4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}