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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a59d44a18213a1548398a70a85dfba6922d739faf0ad0bc9926cdd434319fff' 
  AND token = 'E5dyNFb/9cK1BDKrVmRv05zgqh+Z+Q4WXgmbeaR+x4E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}