SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'adc4d99cff271571b4a43463c2ec2a91e30fe53b700de81e60aec0cf780b5288' 
  AND token = 'azyhFvg7Bw+IkZA6xSHaamYKF5XUcxeyeDQ+UMceDT0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}