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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f77799f3e820f504d779d2d9444f3fe7fb7d70444ebf31001eb75a307266a7f5' 
  AND token = '+c2exH7h89jmKblqtBctXgQjEW1qaK0rvP0eX7b18dI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}