SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '58729f7430a1bec0f7fec099581dbb586019e066ef7a1b16c7fda6d1016333ac' 
  AND token = 'UQfg/kusALkW7rsfUtCxo2APaQTKzEGVsTWd3PjxGns=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}