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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '065f842413793ee977bbed54afad9dfceac07576545ea5d81a15ea1982897513' 
  AND token = 'aCiSV9BgSDdoBdDZTG7BUa1SQrXGvKxUzGcH9FmuXig=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}