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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2aae7bc41fc1b4315aee8c3886dbb651e9fd2ac9dfd5402e0443dc62dda726bf' 
  AND token = 'o73LBIwOAAoLmvS//DIFv9hAfECDBjOK0AXjprFrQUk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}