SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f0f2eb4d121d9b55e85082139a55a9691420c358f50023e632bcec216726823' 
  AND token = 'BZhWErSSbTmLpnEeoD9l1m8ku+Q/SnA71+20W+uEajc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}