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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1344f58bf32d272a022f9fcaa601af2205ca7ec12f0cacfdade23fb9cc4d77a6' 
  AND token = 'r2hKV1C2bHXnrsWHkF2WFFROR/cJq3PnixlfOWCVzGw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}