SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b981b3fc2d2154b5ba06062fe153b875ef8fd90bec1ac8d4155f48524ea2784' 
  AND token = 'qsNaT8Jbipq1FtrGdbIwYi76x5HlUacSXQHsJmaGQ5g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}