SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '262ea47d1599d10a6cc53ff8474c6f51111da96076ae345a9822f4233db0038b' 
  AND token = '+E6p7MidY0JBF0+ercq+ox6KKU2kKtLmszbmfFyeAzw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}