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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f8f728f900e065cd38c806f1b9020152910412d81d7ed620f4bdb5e2f4fd358' 
  AND token = 'g0UkkVj/EKl94TM7jM+IvsxL+kUAdtung24xKpWH+ZQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}