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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8df03da41bc95a326bead4fcbf53854f3b244dcf7fe1532c8de24ceac6e1b4f4' 
  AND token = '3iGtxy1bcu/LHVyzWom9zbXcD05I4hv4ddo4P5QPUXo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}