SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ccf8ade69d904649e71fb07808b5d46574316e9878ab1e62262f6b099451b599' 
  AND token = 'BVQWzjh/4nIDPjLil+LAAeM4WVBiswfcUyiKAHxTVA4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}