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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '398db6a62d60c802d6a8105e255b20efeaf61de8b0affec33dbb9119405b8f9c' 
  AND token = 'SJSjT29yyJ+qrUmbJW4aaNnS1m8rJiwL69wzp1Lmizo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}