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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af7403d9269495a6f5c49d49b537599fbe8e37cf7d18cbdadedda72e2ecf56a0' 
  AND token = 'eB/VxtPmW3MCsvDjGvYjMGvpNF3dXhNvTQrn5A02HBA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}