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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b740f72749428fac8b252ae1b8f5b062f3a0d3cc64d7bfd88f449634f66b80d' 
  AND token = 'JXfpkN+eQQxaxlkss/r2f8HMhsbPdR3mtGLEOT7wpbw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}