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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0472e22b74abb19e5369320e8c2fe0934809338607f0463a80bf226c57aca9f7' 
  AND token = 'k9ddEMFW4aE0b7tCvmw6huV/l3Y6TX14u9jrY4xDZR4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}