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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51f2960a2ce4ca4a9e59a90c10e30000c0b0adac9427a5c869a20f1cefd0b037' 
  AND token = '7VAC8+ZVlJZhERC2de0PO/bPP0+AWChsqZZxOziUMwo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}