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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48ab36700a8b8aac150a292c90b63cd1974194c1e6881e9fb4818fa2a4fb2a9a' 
  AND token = 'TlFhp5Ur0WAHamsfMLK+tE9CMRmuR4wLPMOd3zLRarM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}