SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45301bdf426a17c31f797d912069aeb385be7b2e18c388cd9d144be5adb99854' 
  AND token = 'PPLb05w3mj8lqd2jYnHHRWuGIBspG8LO7FNR6AYMM2E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}