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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2e0965a033e99bfcf059a69234b787c4c369e8d8f56dd1232f8e8c384fb87af' 
  AND token = '46dnc8cUaPuoU1tj8dASgigNtc/DKT3msc84NH3NsAA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}