SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a228da77c216fc0fe9004eaef4ae0da8c694032dc6905e0fefd0e8e2b18d4a1' 
  AND token = 'MY5LAGmstqX7pGRO1qFRRquZyqDH7JzSTLZ8AtB9vyY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}