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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d7565880a487ef759d7c604575bd878372e3613e18abca78665b8ade0a3af09' 
  AND token = 'PzZg2pkTRH8dNgKpMeuGzn062X1TCt7xel82lSMyUJA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}