SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '68bfd52831cf93787555a6c7355609cf60dde183ba60ebd423704c594f023c1d' 
  AND token = 'PVEEp5ZspwX27u/jDleseuIv5wO0HWDx/XFWA89WxwY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}