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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b82be50dec1dd470bdbc07016a08dd048bebc5f10ac7bb718dbdb7369123ceb0' 
  AND token = '48TpxbExYyDrRTsx6ffa5SGOli2NnICqUGbU3rvmIH8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}