SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf890af3c49ccf5ffe2dc4048bd513a534b19dd813be7a6aad3b5d81d27a79e2' 
  AND token = 'F63xVhiEoqvkIiVrSrdhGa1e8WrJGJjm0UxFK4XMnm0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}