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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b8c85794de9c6d2fdb0c98fb30dc1f80fdd1288682c1bd04aba211cb14b5a86' 
  AND token = 'xTMsJGyIoh6lB6eJLlAr7oupPsLst4ceX57p6C2EUPY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}