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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81d10c334e8aac31138791eee4ff64020c9bf2739c9fbf4ccc4e69d0c4923e6f' 
  AND token = 'qX3b0ch11dq4FJXZTf4FEd4RcxYHpl+S7cR0jGccFzk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}