SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '819d54c6a2b3fb7bf36e8d43f620060fc15d639b56254c41451fb1a1d9a2c8af' 
  AND token = 'DenK/3s+fSv4PjQ3t1G4YF1R3oW0iBnqD51aHZ/oFzs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}