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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '543b21a603f8e424e5e10c9f8325fb6b79d56bba03c2c2516448a170d060bfd8' 
  AND token = '7G6oebQIOCPUzzveadDRag3YFDPP8ecabmhoxFWk7+s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}