SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f224bffafc8243a5432c196317dc00f3b388ed97cde6c6b76fb317d75c31646c' 
  AND token = 'vipum+nBx3JOzWKtkX/7TjdxxHVQlaieeTfJUBFPquY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}