SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74d5420113023e73441a3226dcc9554c457e1f10e558b09b739acb3c3000f57d' 
  AND token = '/l3tjtzrlAjJ9ZN8nwZGN5vg9jn+l+UmoMQpkbO93+0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}