SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '86b7c4e114c5ab1ef8c660d4d2758f43dffa0a7236d4c30406cad464ae8c9976' 
  AND token = 'NyFMa5Q0y8PsZJX2eVgwiU8CguaY0yUsW06yvMSm+k0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}