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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e500c9754174861bc196634700384e25fd6da404e432c0552cce2a3b5a4c34d4' 
  AND token = 'yVzB6z419uFzgbI5DQ2SsIiuOQo/GYkKz6IHLyR2Za8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}