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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4423df34b52bce822643208729478b7fb2425ae4886c0048176d48e0cdf40a5' 
  AND token = '7wKv68nA7XK17pH7pwXuq1oPHPt03/6rcHUaqFykgNM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}