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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ccca921246eb2c600bc83414511f5f51aeed316e52ff4dd74bb458987ee0c47' 
  AND token = 'UhoLQYZIJ2Q1H/PT/LkFbdw4W37RQA7SdZW5VxqIo9M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}