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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6622b72e03093da983849d0d1390976e291714bfe94f7a17dc36c3bed4939a07' 
  AND token = 'aU9bUMQSIw6WtD7Zl25eTocovdo8+gIrr40TZtdFQjE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}