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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c884881bd09f43ac88c31662f762c25ae2534d84225c42009045723961ee0b72' 
  AND token = 'nf8ZfNwU2ZDpD8frJxK5CpBxSQC9781ERbWO85CeBUY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}