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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29722f525cd606163c894281d73fe7dbbf7b8f22937383424dcb0b0cbb8b1bbd' 
  AND token = 'YrEJz0+LnUX+I3hWxHy7GABHYbBbzGk4K6GLovIHEaM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}