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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72d4f5d7eac5c734db4f084b27c6049590056ad1ce22d39181646c1df8f286a6' 
  AND token = 'cJ0JaFf8GF04ivbnJHy9COQRNgyD6xSzfebqyJ7PW5U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}