SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8752dbfe557bb1d8a698ce4e8070fdfa783a44a36ce941cabad755a9193003ca' 
  AND token = '+2qnhSdsP6GXpCzwMt5k2E7a+1k0HuPbAVIdYz/F6oA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}