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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '98100e45b87a52cb9027bb227f10318b4b281e7d1c905ea28cb4bdcd0465d401' 
  AND token = 'sAsWy/gJ8LPdjGp7EVV38/bjF0uuXhs3N5fpHv62WW4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}