SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8d410746ebf557c57cefd7c178525e7ea6f737c114573dd3afb5bea919c5133' 
  AND token = '/iygoqRKJKXicGWOTjvOai49K1XaEZZUKdKZu3/NW0o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}