SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5bf743edf717b694d59dbbc67c626a9b091768cf023cd01517f835bd293c0e20' 
  AND token = '0Dzjb4YhuKdj4qP6p0490iZcEJ+O0Ur1mGnOY7f9nW4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}