SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8083e929beb3aedade3a54c202742d57b9633a1c1996acb92a350995ae644e04' 
  AND token = 'kkSM7+FfV5hLoT8NArY71rdXf/kcL6GLAewxbk2SnR0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}