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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4121791aa436fedd31cb3ae5f3726c893bb7d0e8ae1e657eb7c70a2accd5e499' 
  AND token = '4AJ/kTjblb1k0JXW+Rmf8Jd+ZQhp0lR53saZmNGbuqA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}